Barcelona and Real Madrid face tough rivals that will put their unbeaten runs in serious jeopardy. Here's how the games will unfold this weekend.

Matchday 4 in the Spanish Primera División will bring some interesting matches for fans watching at home.

Getafe, Valencia, Real Madrid and Villarreal get to matchday 4 with the same number of points (7), but Los Azulones and Los Blancos will try to take the top spot of the competition with one game in hand. Barcelona is one point behind the four teams mentioned previously, and the Blaugrana side could reach the top spot if they can manage to beat Sevilla this weekend and the four "leaders" suffer any mishaps this weekend.

Surprisingly, the match between Barcelona and Sevilla will not be the only one to keep an eye on, as Atlético Madrid will host Villarreal in quite an exciting clash. Los Rojiblancos dropped two points against Huesca in their midweek match, but Suárez and Co. might find it easier to beat a team that was recently blown out of the water by Barcelona.

Team news - Who's in and who's out?

Atlético Madrid - Sime Vrsaljko (injured); José Giménez (doubtful).

Barcelona - Marc-André Ter Stegen, Samuel Umtiti (injured); Clement Lenglet (suspended); Junior Firpo (doubtful).

Real Betis - Dani Martin, Victor Camarasa, Francis (injured); Aissa Mandi (suspended); Claudio Bravo, Andrés Guardado, Diego Lainez (doubtful).

Real Madrid - Mariano, Toni Kroos, Eden Hazard (injured); Eder Militao (doubtful).

Sevilla - Sebastién Corchia (injured); Carlos Fernández, Bryan Gil (doubtful).

Villarreal - Alberto Moreno, Ramiro Guerra, Francis Coquelin (injured); Pervis Estupiñán, Rubén Peña, Alfonso Pedraza (doubtful).

Key stats ahead of Matchday 4

  • Real Madrid are unbeaten in their last 14 La Liga games.

  • Atlético are undefeated in their last 18 La Liga games.

  • Barcelona have four goals in their last three games against Sevilla at Camp Nou Stadium.

  • Sevilla have not lost any of their last 17 La Liga games.

  • Real Betis have won only one of their last 14 away games in La Liga.

Coach's quotes ahead of Matchday 4

Atlético boss Diego Simeone spoke in his pre-match press conference about how he will handle Luis Suárez and Diego Costa as the team's starting striker. Despite Suárez's impressive numbers, it seems that Simeone has other plans on how to handle that tricky situation.

"I spoke to Costa before the season started and he knows what I want from him and what the team needs, Luis came in only one week ago and we are really looking forward to his contributions on the pitch. We will keep working with the general idea we had on that subject," Simeone said.

La Liga Matchday 4 - October 3-4 fixtures